Pongo and Perdita have a litter of 15 puppies. Cruella De Vil takes a fancy to the pups, and wants to get hold of them, as well as more pups, to make herself a lovely Dalmatian skin coat. Cruella hires some thugs to kidnap the pups and hold them at her mansion. Pongo and Perdita enlist the help of the local dogs London to find and rescue them.